Change in HLA testing procedure from 1 November 2021

Dear Contracting Authorities,

we would like to inform you of a change in the HLA testing procedure. As of 1 November 2021, we are introducing the use of new AlloSeq kits for HLA genotyping within the granted flexible scope of accreditation by NGS. This change will allow us to process the lower quality DNA that is obtained in some patients referred for HSCT.

At the same time, these kits also allow testing for additional genes in the HLA region, which can be introduced into routine testing if you wish. These include the classical HLA class II: HLA-DRB3-5 and HLA-DPA1, as well as the non-classical HLA-E, F, G, H and the MICA and MICB genes.

If you are interested in testing any of the above genes, please contact me by e-mail.

Thank you,

Ing. Milena Vraná

Prague 27. 10. 2021