Quick contact
Head of Science and Research Division
Tel:+420 221 977 208
Deputy head of Science and Research Division
Tel:+420 221 977 269
Tel:+420 221 977 364
Secretary
Tel:+420 221 977 247
Institute of Hematology and Blood Transfusion
A number of blood disorders is associated with altered iron uptake, processing and storage in the human body. The iron is an essential component of many proteins participating in virtually all metabolic processes. On the other hand, iron produces free radicals which trigger or at least risk factors for many diseases. The understanding of iron resorption and of its use in the body is thus crucial for the development of new drugs and therapeutic approaches, e.g. for the treatment of anemias or hemochromatosis (hereditary iron overload).
In particular, we have focused on the peptide hormone hepcidin, the main regulator of the iron storage and release. We have identified its main transporters in the serum and we aim to explore the possibility to regulate the iron metabolism by manipulating hepcidin levels in the body. The research in this field is performed in cooperation with the Institute of Pathological Physiology of the First Medical Faculty of Charles University and is supported by the Grant Agency of the Czech Republic (grant project No 15-14200S).
Head of Science and Research Division
Tel:+420 221 977 208
Deputy head of Science and Research Division
Tel:+420 221 977 269
Tel:+420 221 977 364
Secretary
Tel:+420 221 977 247
Ambulance
Mo – Fr:
7:00–18:00
Weekends:
9:00–13:00
Donors
Mo – Fr:
7:00–10:30
Visitors
Inpatient department
Mo – Fr:
13:00–18:00
ICU and Transplant unit
Mo – Fr:
14:00–17:00
Ústav hematologie a krevní transfuze
(Institute of Hematology and Blood Transfusion)
U Nemocnice 2094/1
128 00 Praha 2
The nearest underground station: Karlovo náměstí (line B)
The nearest tram station: Karlovo náměstí (10, 16, 22), Moráň (3, 6, 10, 16, 18, 24)
The nearest bus station: U Nemocnice (148), Karlovo náměstí (176)