Quick contact
Head of Science and Research Division
Tel:+420 221 977 208
Deputy head of Science and Research Division
Tel:+420 221 977 269
Tel:+420 221 977 364
Secretary
Tel:+420 221 977 247
Institute of Hematology and Blood Transfusion
Hereditary spherocytosis (HS) is caused by mutations in cytoskeletal proteins of erythrocytes. Lowered expression or altered function of the cytoskeletal proteins lead to the loss of the normal shape of the erythrocyte and to lower resistance to osmotic pressure. Hemolysis and premature retention of erythrocytes in the spleen result in anemia.
In the framework of the Centre for Rare Hematopoietic Disorders, we have been introducing methods for specific diagnostics of hereditary spherocytosis: eosin-maleimide binding test (EMA, a fast and relatively specific screening method for HS) and the detailed analysis of erythrocyte skeletal proteins using gel electrophoresis.
Head of Science and Research Division
Tel:+420 221 977 208
Deputy head of Science and Research Division
Tel:+420 221 977 269
Tel:+420 221 977 364
Secretary
Tel:+420 221 977 247
Ambulance
Mo – Fr:
7:00–18:00
Weekends:
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Donors
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7:00–10:30
Visitors
Inpatient department
Mo – Fr:
13:00–18:00
ICU and Transplant unit
Mo – Fr:
14:00–17:00
Ústav hematologie a krevní transfuze
(Institute of Hematology and Blood Transfusion)
U Nemocnice 2094/1
128 00 Praha 2
The nearest underground station: Karlovo náměstí (line B)
The nearest tram station: Karlovo náměstí (10, 16, 22), Moráň (3, 6, 10, 16, 18, 24)
The nearest bus station: U Nemocnice (148), Karlovo náměstí (176)